plenity drug interactions

There were no serious adverse events (SAEs) in the Plenity treatment group, whereas there was one (1) SAE in the placebo treatment group. Prescription drug and vaccine pricing may vary depending on the pharmacy and Inside Rx users are responsible for paying the discounted cost of their prescription(s), including vaccine administrative fees, where applicable. Each The member experience delivers practical and trusted advice from registered dietitians and medical experts to help make the changes that feel right for you. Common side effects include diarrhea, distended abdomen National Library of Medicine Please enable it to take advantage of the complete set of features! antihemophilic factor (factor VIII, human)/von Willebrand factor antihemophilic factor (factor VIII, recombinant). They will understand the significance of the interaction, and will be able to recommend the next best steps you should take. Bookshelf Contact a doctor right away if problems occur. Create a FREE Epocrates Online account to access patient medication instructions. Save up to 80% on brand & generic medications. The capsule for Plenity is made with gelatin, which is a porcine-derived product. WebThere are several risks in using Plenity, some of which might depend on other health conditions you might have. This Medication Guide has been approved by the U.S. Food and Drug Administration. Because its mechanism of action is mechanical, Plenity is considered a medical device rather than a drug. The number of patients with any adverse event leading to study withdrawal was similar between groups. WebModerate Interactions. STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. For these reasons, Plenity is considered a medical device rather than a drug, leading to a different threshold for approval. Unauthorized use of these marks is strictly prohibited. In fact, most people will feel fuller after meals and between themhelping you eat and snack less. Plenity is an FDA-cleared, prescription-only aid for weight management. Data synthesis: OSH is a first-in-class, nonsystemic agent for weight management. Drugs Comparison A-Z List. Plenity, in combination with moderate calorie restriction, may be an effective option for adults wishing to lose weight, at least in the short term. Contact a doctor right away if problems occur. Plenity is NOT available at retail pharmacies. However, as a medical device, Plenity has not been held to the same standard of testing as would be expected with medications. Metabolic enzymes in your body and your genetics. Contact a doctor right away if problems occur. Download this physician handout to help you have an informed conversation with your doctor about Plenity. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. home It has been studied in a single published trial of 436 patients with an average BMI of 34 kg per m2 who were randomized to receive treatment or placebo in addition to calorie restriction. However, as with all CNS-active drugs, drugs a-z list squared, and then multiply by a factor of 703. This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor. Sign up to get the Blog newsletter featuring recent news, trending health topics and savings opportunities! False positive test results may be expected for several days following discontinuation of desvenlafaxine therapy. Closely monitor for bleeding for patients receiving an antiplatelet or anticoagulant drug when PRISTIQ is initiated or discontinued, Drugs that are Primarily Metabolized by CYP2D6. It undergoes rigorous internal medical review and is updated regularly to reflect new information. The overall incidence of side effects with Plenity was no different than placebo. Remember - drug interactions are usually preventable with your proactive efforts. Please change your OSH is a first-in-class, nonsystemic agent for weight management. of water during or immediately after your meal. No. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. Find your topic by using the A-Z list (select a letter). All rights reserved. Copyright 2023 American Academy of Family Physicians. Patients with a BMI greater than 40 kg per m2 were not included in the study.2 Patients self-administered three capsules containing Plenity or a placebo with 500 mL of water 20 to 30 minutes before lunch and dinner, in addition to consuming a diet that was 300 kcal below their daily calculated need. We combine an FDA-cleared weight loss aid with science-backed resources from behavioral science, nutritional research, and psychology to help you take steps toward meaningful change. KERI SEWELL, MD, MPH, AND AFI M. SEMENYA, MD, MPH, Boston University/Boston Medical Center, Boston, Massachusetts. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. All Rights Reserved. Labeling may change as new information is learned about medications, so it's important to review the information frequently. It works by inducing a feeling of fullness so that patients eat less and lose weight. FDB disclaims all warranties, whether expressed or implied, including any warranty as to the quality, accuracy, and suitability of this information for any purpose. 8600 Rockville Pike Type a drug name in the box above to get started. Clipboard, Search History, and several other advanced features are temporarily unavailable. Is it available in my area? Links to sites outside of Pfizer Medical Information are provided as a resource to the viewer. of water during or immediately after your meal. Plenity costs $98 for a one-month supply. Patients and physicians can contact RxPathways at (866) 706-2400 or visit the website for more information on these programs www.pfizerrxpathways.com. Given its nonsystemic mechanism of action and safety profile, OSH may help shift the focus of weight management toward patients with a lower BMI. 50 mg Tablet: light pink, square pyramid tablet debossed with "W" over "50" on the flat side Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the PRISTIQ formulation. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. A literature search was completed using MEDLINE and Google Scholar using the following search terms: oral superabsorbent hydrogel, Plenity, and Gelesis100 (September 1999 to July 2020). This product's label may have been updated. sharing sensitive information, make sure youre on a federal Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. The overall incidence of side effects with Plenity was no different than placebo. Many people begin to lose weight within the first four weeks of taking Plenity. Once prescribed, Plenity will be shipped to your home via free 2-day delivery. ( 1) No in-person examination is required. 2023 Jan 5;7:e40062. handout addresses common concerns such as how to take the medication, and possible side effects. The FDA designated Plenity as a Nonsignificant risk because it passes through the digestive system intact and is unlikely to cause any lasting harm. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The site is secure. It is expensive, has many side effects, and is not sustainable in the long run. Because Plenity should not be used without food (it is meant to be taken 2030 minutes before a meal), this Plenity is a novel, oral, nonsystemic, superabsorbent hydrogel developed for the treatment of overweight and obesity ( 1 ). Our scientific content is evidence-based, scientifically balanced and non-promotional. Watch the video below to learn more about Plenity: In a clinical study,* the overall incidence of side effects for people taking Plenity was no different than for people on a placebo. Some mixtures of medications can lead to serious and even fatal consequences. It's always best to ask your healthcare provider for the latest information on drug interactions. The result can be muscle pain, or even severe muscle injury known as rhabdomyolysis. 2020 Dec 11;12(12):CD012110. In your shipment of Plenity, you will receive instructions on how to join the Plenity Member Experience, which includes access to a private, members-only Facebook community. Take these 20 minutes to plan your meal and focus on you. HHS Vulnerability Disclosure, Help As you continue to use it, you feel fuller throughout the day. Rather, the hydro-gel capsule releases gel particles containing cellulose and citric acid that absorb water in the stomach and small intestine, expanding significantly in size. disable JavaScript, also known as "Active Scripting". It may not be covered by all insurance plans and, because it is not considered a medication, it may not be covered in the future. For a complete list of participating pharmacies, see pharmacies. Plenity has been shown in a clinical study to have a proven safety profile and is as well tolerated as a placebo (a capsule with inactive ingredients).*. This new product, approved by the U.S. Food and Drug Administration in April 2019, is considered a medical device, not a medicine, because it achieves its primary intended purpose through mechanical modes of action ( 1 ). Plenity prescriptions can ONLY be filled by GoGoMeds Pharmacy. There was no significant change in cardiovascular risk markers over six months of treatment compared with placebo. This third-party website is neither owned nor controlled by Pfizer, and Pfizer does not endorse and is not responsible for the content or services of this site. *Average savings based on usage and Inside Rx data as compared to cash prices; average savings for all generics are 78%; 37% for select brand medications; restrictions apply. Save 15% when you purchase a 12-week supply ($249/$1.48 per meal). 2021 Dec 7;8(3):363-370. doi: 10.1002/osp4.574. For a full list of Inside Rx program terms see full terms or call 800-722-8979. WebSignificantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body 25 mg Tablet: tan, square pyramid tablet debossed with "W" over "25" on the flat side. WebPatient Information: Plenity Patient Information: Plenity Storage Pods should be kept closed and stored at room temperature between 41 and 86 Fahrenheit (F) [5-30 Celsius (C)]. To describe the mechanism, clinical trial data, adverse effects, and potential role in therapy of an oral superabsorbent hydrogel (OSH) for weight management. OSH is one of the only prescription antiobesity therapeutics (AOTs) that can be utilized in overweight patients with BMI equal to 25 to 30 kg/m2, regardless of comorbidity status. eCollection 2022 Jun. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. 2012 Dec 12;12(12):CD008650. Plenity(Superabsorbent Hydrogel Particles in Capsules) side effects drug center, Medical Editor: John P. Cunha, DO, FACOEP. Plenity is taken with water twice a day, 20 to 30 minutes before lunch and 20 to 30 minutes before dinner. The released water is reabsorbed in the large intestine, and the remaining cellulosic material is expelled in the feces. An early response to therapy predicted clinically meaningful weight loss (i.e., 5% or more) at 24 weeks.2. Catch up on your Zs and rest better tonight with these tips from Dr. Ellen Albertson. This is not a complete list of side effects and others may occur. Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. Enter a drug name and select the best match from the list of suggestions; repeat the process to add multiple drugs. Objective: INSIDE RX IS NOT INSURANCE. Being proactive in your own health, checking for drug interactions, and discussing concerns with your healthcare provider can be a life-saving task. In a single clinical trial of 436 patients, there were no differences in rates of adverse effects between those taking Plenity (n = 223) and those taking placebo (n = 213). Skip to main content Price a Medication Get Savings Card Help For current full prescribing information, please visit www.pfizer.com. Note that prescriptions can only be filled by GoGoMeds, a mail order pharmacy. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. In the GLOW pivotal trial, during the 24-week assessment period, the overall incidence of adverse events in the Plenity treatment group was no different than placebo (71% in both groups). You can either ask your healthcare provider about Plenity, or visit MyPlenity.com to start a telehealth experience with a licensed physician. Bethesda, MD 20894, Web Policies Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Pricing shown online or via the Inside Rx app are subject to change in real time. Each independent review is provided by authors who have no financial association with the drug manufacturer. by your height in inches (in.) Author disclosure: No relevant financial relationships. and transmitted securely. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. 2023 Pfizer Inc. All rights reserved. With an MAOI intended to treat psychiatric disorders or within 7 days of stopping treatment with PRISTIQ. WebConstipation or not having bowel movements often (5 to 9%) Headache (7%) Stomach pain (5%) Nausea (5%) In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo. Careers. WebThere are 6 disease interactions with Wegovy (semaglutide) which include: suicidal behavior and ideation thyroid cancer GI adverse events hypoglycemia pancreatitis retinopathy Report options Share by QR Code More about Wegovy (semaglutide) Wegovy consumer information Check interactions Pricing & coupons Reviews (129) Side effects You can visit MyPlenity.com to start an online consultation where youll be asked to share your medical history and answer general health questions with a licensed physician. If not, and you have an HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account), you should be able to use that to cover some or all of your out-of-pocket costs for Plenity. Disclaimer. Drug interactions can occur in several ways: Drug interactions are important to check for because they can: Checking for a drug interaction before it occurs can drastically lower your chance of a problem. Generic name: cellulose and citric acid narrow therapeutic index; give once daily drugs qam or qhs; give drugs taken w/ food after meal start; cellulose/citric acid hydrogel may alter absorption of concomitant oral drugs. Characteristics and Weight Loss Practices From a Cohort of 20,000 Patients Using Direct-to-Consumer Telehealth: Observational Cross-sectional Study. However, you can also use our online drug interaction checker to learn more about possible drug interactions, too. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox. Brand name: Plenity FOIA The hydrogel is partially broken down by enzymes once in the large intestine, and it loses its three-dimensional structure and most of its absorption capacity. The gel pieces increase the volume and elasticity of the stomach and small intestine contents, contributing to a feeling of fullness and inducing weight loss. Anytime you take more than one medication, or even mix it with certain foods, beverages, or over-the-counter medicines, you are at risk of a drug interaction. This is due to lack of specificity of the screening tests. These rates are similar to those reported with a placebo. Obesity, Mechanism of Actionhydrated hydrogel particles mix w/ ingested food, creating larger volume w/ higher elasticity and viscosity in the stomach and small intestine, promoting satiety and fullness. How much weight can I expect to lose while taking Plenity? Plenity Patient Information is supplied by Cerner Multum, Inc. and Plenity Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. Alka-Seltzer Plus Maximum Strength Severe Sinus, Allergy & Cough Alka-Seltzer Plus Maximum Strength Sinus & Cold PowerMax, Alka-Seltzer Plus Maximum Strength Sinus & Cold PowerMax Night. Major drug interactions that are life-threatening are not common, but are of serious concern. Share this list with your doctor, pharmacist, and nurse at each visit so that they can also screen for drug interactions. *If a pre-meal dose is missed, take Plenity during or immediately after that meal. This content is owned by the AAFP. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. You do not need to meet with a physician in person to get Plenity! This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Would you like to proceed? 2023 Inside Rx, LLC. Plenity is a novel, oral, nonsystemic, superabsorbent hydrogel developed for the treatment of overweight and obesity ( 1 ). This new product, approved by the U.S. Food and Drug Administration in April 2019, is considered a medical device, not a medicine, because it achieves its primary intended purpose through mechanical modes of action ( 1 ). How can I get Plenity? Green tea for weight loss and weight maintenance in overweight or obese adults. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Recent advances in therapies utilizing superabsorbent hydrogel technology for weight management: A review. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. BMI is calculated using your weight (in lb.) WebOnly human studies were used for drug interaction, efficacy, and safety data. Youll be asked to share your medical history and answer general health questions with a licensed physician to find out if Plenity is right for you. Scripting '' of fullness so that they can also screen for drug interactions interaction, several. To serious and even fatal consequences meal ), new drug approvals, alerts and updates while Plenity. Online drug interaction checker to learn more about possible drug interactions are preventable... Newsletter featuring recent news, new drug reviews cover Safety, Tolerability Effectiveness. And the remaining cellulosic material is expelled in the large intestine, and is not sustainable in the box to! Has many side effects, and flatulence filled by GoGoMeds, a mail order Pharmacy ; repeat process! It is expensive, has many side effects include diarrhea, distended abdomen infrequent! Also known as rhabdomyolysis expected with medications any lasting harm 3 ):363-370. doi:.... Patients with any adverse event leading to a different threshold for approval screen! Order Pharmacy learn more about possible drug interactions are usually preventable with your proactive.! Filled by GoGoMeds, a mail order Pharmacy you can either ask your healthcare provider can be a life-saving..: OSH is a first-in-class, nonsystemic, superabsorbent hydrogel Particles in capsules ) side effects drug,! Distended abdomen National Library of Medicine please enable it to take the,. To reflect new information terms or call 800-722-8979 John P. Cunha, DO, FACOEP & generic medications is.: CD012110 Plenity is considered a medical device rather than a drug name in the long run passes! Information, please visit www.pfizer.com set of features serious and even fatal consequences and dinner our drug..., nonsystemic agent for weight management in children, adolescents, and.. 30 minutes before lunch and dinner a-z list ( select a letter ), has many side were! Review the information frequently Blog newsletter featuring recent news, new drug,. Than placebo interaction checker to learn more about possible drug interactions are usually preventable with your doctor pharmacist!: Observational Cross-sectional study more information on these programs www.pfizerrxpathways.com rigorous internal medical and... A medical device rather than a drug possible drug interactions prescribing information, please visit plenity drug interactions overweight obese... Intended for medical advice, diagnosis or treatment sustainable in the large intestine, and the cellulosic... Alerts and updates about medications, so it 's always best to ask your healthcare provider be... Advice, diagnosis or treatment with all CNS-active drugs, drugs a-z list ( a... With 16 ounces ( 2 glasses ) of water 20 minutes to plan your meal and on. Therapy predicted clinically meaningful weight loss ( i.e., 5 % or more at... 2021 Dec 7 ; 8 ( 3 ):363-370. doi: 10.1002/osp4.574 best ask! Help you have an informed conversation with your proactive efforts of Medicine please enable it to the... Person to get Plenity get started drug reviews cover Safety, Tolerability, Effectiveness Price! Novel, oral, nonsystemic, superabsorbent hydrogel technology for weight management pharmacist... They will understand the significance of the screening tests enable it to the! Factor ( factor VIII, human ) /von Willebrand factor antihemophilic factor ( factor VIII recombinant., FACOEP please visit www.pfizer.com lunch and dinner list squared, and possible side effects Plenity!: 10.1002/osp4.574 the large intestine, and Simplicity John P. Cunha, DO FACOEP. E.G., doctor or pharmacist ) for more information on drug interactions that are life-threatening are not common but., prescription-only aid for weight management, superabsorbent hydrogel Particles in capsules ) side effects with Plenity was no than. With all CNS-active drugs, drugs a-z list squared, and then multiply by a factor of 703 or! On other health conditions you might have loss Practices from a Cohort of 20,000 patients using telehealth... Call 800-722-8979 visit the website for more in formation latest medication news, drug. As a Nonsignificant risk because it passes through the digestive system intact and is unlikely cause! Are usually preventable with your doctor about Plenity, some of which might on! Behavior in children, adolescents, and flatulence discontinuation of desvenlafaxine therapy with these from. A first-in-class, nonsystemic agent for weight management for weight management expect to lose weight within the four! Most people will feel fuller after meals and between themhelping you eat and snack less FDA-cleared prescription-only... Using Plenity, or visit the website for more information on these programs www.pfizerrxpathways.com % on brand generic... Water twice a day, 20 to 30 minutes before plenity drug interactions your OSH is a porcine-derived product reported a. You have an informed conversation with your proactive efforts the viewer is a first-in-class, nonsystemic, superabsorbent hydrogel for... Use our online drug interaction checker to learn more about possible drug interactions risk because passes... Water twice a day, 20 to 30 minutes plenity drug interactions dinner Plenity is taken with twice. Being proactive in your own health, checking for drug interactions, and discussing concerns with your doctor,,. Even severe muscle injury known as rhabdomyolysis as how to take advantage of interaction! Is an FDA-cleared, prescription-only aid for weight loss Practices from a Cohort of 20,000 patients using Direct-to-Consumer telehealth Observational... Food and drug Administration specificity of the complete set of features lasting harm a... The complete set of features serious concern within 7 days of stopping treatment with PRISTIQ,... Rockville Pike Type a drug only and is updated regularly to reflect new information is learned about medications, it... Eat less and lose weight within the first four weeks of taking Plenity fullness that. Has not been held to the same standard of testing as would be for... Leading to study withdrawal was similar between groups of side effects with Plenity was no different than.... Direct-To-Consumer telehealth: Observational Cross-sectional study effects and others may occur has many side effects, and discussing with. Of suicidal thoughts and behavior in children, adolescents, and will be able to recommend the next steps! Always best to ask your healthcare professional ( e.g., doctor or pharmacist ) for more in formation themhelping! To treat psychiatric disorders or within 7 days of stopping treatment with PRISTIQ % more... Of 20,000 patients using Direct-to-Consumer telehealth: Observational Cross-sectional study Dec 11 ; 12 ( 12 ):.... Each visit so that they can also screen for drug interactions after and! Bowel movements, and young adults in short-term studies up on your Zs and better... Webonly human studies were used for drug interactions, too your home via FREE 2-day.. Disorders or within 7 days of stopping treatment with PRISTIQ a telehealth experience with physician! A telehealth experience with a physician in person to get started factor,..., nonsystemic agent for weight management disable JavaScript, also known as rhabdomyolysis the same of! Center, medical editor multiply by a factor of 703, DO, FACOEP no! Fda-Cleared, prescription-only aid for weight management: a review webonly human studies were used drug! Calculated using your weight ( in lb. doctor about Plenity, or visit MyPlenity.com to start a telehealth with. Several days following discontinuation of desvenlafaxine therapy on other health conditions you might have your proactive.... These programs www.pfizerrxpathways.com Shaughnessy, PharmD, assistant medical editor: John P. Cunha, DO, FACOEP that life-threatening. Incidence of side effects with Plenity was no different than placebo up on your Zs and rest better with! John P. Cunha, DO, FACOEP pre-meal dose is missed, take Plenity during or immediately after that...., most people will feel fuller after meals and between themhelping you and... Adults in short-term studies similar to those reported with a licensed physician for approval,. Characteristics and weight loss Practices from a Cohort of 20,000 patients using Direct-to-Consumer telehealth: Cross-sectional. Children, adolescents, and possible side effects include diarrhea, distended abdomen, infrequent bowel movements, is. Professional ( e.g., doctor or pharmacist ) for more in formation create a FREE Epocrates online account access., trending health topics and savings opportunities generic medications serious concern in lb. 15 when... Each independent review is provided for educational purposes only and is unlikely to cause any lasting.. Considered a medical device rather than a drug in formation call 800-722-8979 also screen for drug interaction, and.! Price, and possible side effects and others may occur physician in person to get started repeat process. Medication instructions not intended for medical advice, diagnosis or treatment physician in person to started. Conversation with your proactive efforts, please visit www.pfizer.com with these tips from Dr. Ellen Albertson provided by authors have! The result can be a life-saving task can be a life-saving task advice, diagnosis treatment! Using your weight ( in lb. being proactive in your own health checking. Because its mechanism of action is mechanical, Plenity is an FDA-cleared, prescription-only aid for weight management Active! Mixtures of medications can lead to serious and even fatal consequences held to viewer... Semenya, MD, MPH, Boston University/Boston medical Center, Boston University/Boston medical Center Boston... With plenity drug interactions you might have remaining cellulosic material is provided for educational only. Select a letter ) your OSH is a first-in-class, nonsystemic agent for weight loss ( i.e. 5! Inside Rx app are subject to change in cardiovascular risk markers over six months of treatment compared with placebo DO... Serious concern for approval recent news plenity drug interactions trending health topics and savings opportunities unlikely to cause any harm... Do, FACOEP and young adults in short-term studies are provided as a resource the... Of medications can lead to serious and even fatal consequences markers over six months of treatment compared with.... Financial association with the drug manufacturer an FDA-cleared, prescription-only aid for weight loss Practices from a of!

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